disulfide bonds — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T20470	Edetic acid	Ethylenediaminetetraacetic acid,EDTA	Others
	Edetic acid (Ethylenediaminetetraacetic acid) is a chelating agent commonly used in protein purification, both to eliminate contaminating divalent cations and to inhibit protease activity.		Others
T1085	L-Glutathione reduced	GSH,Isethion,Glutathione,γ-L-Glutamyl-L-cysteinyl-glycine,Glutathion,Tathion	Ferroptosis , Reactive Oxygen Species , Endogenous Metabolite , Glutathione reductase
	L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals. L-Glutathione reduced is a cofactor for certain enzymes and is invo...
T6741	SPDP	SPDP Crosslinker	Others
	SPDP is a short-chain crosslinker, which is used for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. SPDP could ...		Others
TP2325L	Endotoxin Inhibitor acetate	Endotoxin Inhibitor acetate(147396-10-9 free base)	Others
	Endotoxin Inhibitor acetate has a strong blocking effect on bacterial physiological activity, thus producing antibacterial toxin Inhibitor sequences with disulfide bonds and a large amount of lysine. Endotoxin Inhibitor ...		Others
T3161L	BACE-IN-1 acetate	BACE-IN-1 acetate (350228-37-4，Free base)	BACE
	BACE-IN-1 acetate (BACE-IN-1 acetate (350228-37-4，Free base)) has been used as β-site amyloid precursor protein (APP) cleaving enzyme-1 (BACE1) inhibitor in BACE1 inhibitor assay. β-Site amyloid precursor protein (APP) c...		BACE
T11057	DM3-SMe		Others
	DM3-SMe is a maytansine derivative and tubulin inhibitor. It is a cytotoxic part of antibody-drug conjugates (ADCs) and can bind to antibodies via disulfide bonds or stable thioether bonds. DM3-SMe has high cytotoxic act...		Others
T31584	DST Crosslinker	DST Cross linker,DST Cross-linker
	DST crosslinker(disuccinimide tartarate) is an isotype bifunctional, cleavable crosslinker (cleavable by an oxidizer) for applications that require crosslinking cleavability and that do not interfere with protein disulfi...
T35456	(±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane
	(±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane (BMC) is a cyclohexane with two mercaptoacetamido groups. It is used, both in vitro and in vivo, to promote the correct folding of proteins that require disulfide bonds f...
T40153	BAMEA-O16B	BAMEA-O16B
	BAMEAO16B is a lipid nanoparticle that incorporates disulfide bonds for efficient delivery of Cas9 mRNA and sgRNA into cells. In the intracellular environment, BAMEAO16B responds to reduction by releasing RNA, facilitati...
T82255	GsAF-1
	GsAF-1, a peptide toxin with three disulfide bonds, is derived from the venom of the Chilean pink tarantula and has potential applications in the research of moderate-to-severe pain [1].
T17834	DM4-SPDP		Others
	DM4-SPDP, a drug-linker conjugate, integrates the antitubulin agent DM4 with the linker SMCC, facilitating the creation of antibody drug conjugates[1]. Additionally, SPDP serves as a short-chain crosslinker enabling amin...		Others
T11059	DM4-SMe		Others
	DM4-SMe is a cytotoxic part of antibody-drug conjugates (ADCs) and a metabolite of antibody-maytansin conjugates (AMCs) and tubulin inhibitors, which can also be stabilized by disulfide bonds or thioether The bond binds ...		Others
T80078	Calciseptin		Calcium Channel
	Calciseptine, a neurotoxin isolated from the Black Mamba (Dendroaspis p. polylepis) venom, comprises 60 amino acids and is stabilized by four disulfide bonds. It specifically targets and blocks L-type calcium channels [1...		Calcium Channel
TP1971	Pseudo RACK1
	Activator of protein kinase C; attached to cell permeabilization Antennapedia domain vector peptide. Consists of peptide derived from the C2 domain of PKC β linked by a disulfide bridge to the Antennapedia domain vector ...
T77908	Farletuzumab ecteribulin	MORAb-202
	Farletuzumab ecteribulin (MORAb-202) is a highly cytotoxic antibody-drug conjugate (ADC) targeting human folate receptor alpha (FRA). This ADC comprises the humanized Farletuzumab antibody linked to Mal-PEG2-Val-Cit-PAB-...
TP2259	Immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus]		Others
	Immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus] is a fragment on the variable region of the human and mouse immunoglobulin light chain. Immunoglobulins (Ig) are the antigen recognition m...		Others
TP2260	Immunoglobulin M heavy chain (IGHM) fragment [Homo sapiens]		Others
	Immunoglobulin M heavy chain (IGHM) fragment [Homo sapiens] is a fragment (Gly-Val-Ala-Leu-His-Arg-Pro-Asp-Val-Tyr-Leu-Leu-Pro-Pro-Ala-Arg) on the human immunoglobulin micro heavy chain. Immunoglobulins (Ig) are the anti...		Others
T80249	Epsilon-V1-2, Cys-conjugated		PKC
	Epsilon-V1-2, a Cys-conjugated, is a biologically active peptide known as the εPKC-specific inhibitor. It hampers εPKC functionality by obstructing its translocation and the phosphorylation of MARCKS, additionally pertur...		PKC